Molecule discovered to combat baldness

According to Mejor con Salud, a group of researchers at the University of California, Los Angeles (UCLA) has been quietly working for a decade on something that could change the way we deal with hair loss. The result: a molecule they called PP405, capable of "awakening" hair follicles that had already stopped producing hair.

Hair loss affects both men and women and can be due to multiple factors such as stress, the passage of time, hormonal imbalances, or simply genetics. Although there are treatments on the market, few offer a lasting or truly effective solution.

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PP405 acts on a specific protein that, under normal conditions, keeps hair follicle stem cells inactive. By blocking this protein, the molecule reactivates those cells and puts them back into action, resulting in the growth of new, thick, and visible hair—not the fine, weak hair produced by other treatments.

The first human trials were conducted in 2023. Volunteers applied the substance, in the form of a topical lotion, to their scalp before bed for a week. The initial results were positive: hair growth and no serious side effects.

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Although scientists insist it's still too early to draw definitive conclusions, the data was robust enough to be described as "statistically significant." One of the project leaders, Professor William Lowry, confessed that they initially feared PP405 might be too aggressive: "We were worried the molecule would completely destroy the follicles, but we were pleasantly surprised," he explained.

Research will continue with larger studies and long-term trials, but the scientific community is already closely monitoring this finding. Perhaps, in the not-too-distant future, hair loss will no longer be an unsolvable problem.

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